Case report: A 41-year-old male was admitted to hospital due to shortness of breath. We are presenting an unusual case of PS with acute respiratory failure resulting in organ failure and mortality.

Patients with PS could present into general OSA or respiratory failure. Introduction: Pickwickian Syndrome (PS) or obesity hypoventilation syndrome (OHS) is a diagnosis of exclusion with features of obesity, sleep disordered breathing, and chronic daytime hypercapnia. The novel nomogram and online calculator provided an excellent preoperative individualized prediction of OHS in patients undergoing bariatric surgery, hereby potentially assisting clinicians and surgeons in the early detection and intensive monitoring of OHS.

Decision curve analysis further confirmed the nomogram’s clinical usefulness. The nomogram revealed good discrimination, with a C-index of 0.830 (95% CI: 0.784–0.876) (0.8227 through internal validation), and good calibration. The nomogram was internally validated using bootstrap resampling.Ī total of 577 patients were enrolled, and OHS was presented in 17.9% (103/577). The discriminative ability, calibration, and clinical value of the nomograms were tested using C-statistics, calibration plots, and decision curve analysis. Predictors were identified using univariate and multivariate analyses to establish the nomogram. We retrospectively analyzed the data of patients undergoing bariatric surgery between March 2017 and June 2020. We aimed to determine the predictors of OHS and to develop and validate a novel nomogram and online calculator for identifying patients at risk of OHS in bariatric surgery candidates. Obesity hypoventilation syndrome (OHS) is frequently misdiagnosed and undertreated, increasing the risk of perioperative complications.

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